| 18. Round | 23/01/2022 | Arenas de Getxo | - | Peña Sport FC | 6:0 | ||||
| 19. Round | 30/01/2022 | Peña Sport FC | - | Burgos Promesas | 1:3 | ||||
| 20. Round | 06/02/2022 | Racing Rioja CF | - | Peña Sport FC | 1:0 | ||||
| 21. Round | 13/02/2022 | Peña Sport FC | - | CF Ardoi | 3:1 | ||||
| 25. Round | 13/03/2022 | Sestao River | - | Peña Sport FC | 1:0 |  |
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| 28. Round | 02/04/2022 | Peña Sport FC | - | UD Logroñés Promesas | 1:2 | ||||
| 29. Round | 09/04/2022 | UD Mutilvera | - | Peña Sport FC | 3:3 |
Spain