| 5. Round | 28/03/2022 | Unión de Santa Fe II | - | Platense II | 0:4 | ||||
| 10. Round | 15/04/2022 | Racing Club II | - | Unión de Santa Fe II | 2:0 | ||||
| 11. Round | 20/04/2022 | Unión de Santa Fe II | - | San Lorenzo II | 1:4 | ||||
| 14. Round | 05/05/2022 | Argentinos Juniors II | - | Unión de Santa Fe II | 4:0 |
Argentina