| 20. Round | 18/09/2022 | Independiente II | - | Unión de Santa Fe II | 2:0 | ||||
| 21. Round | 22/09/2022 | Newell's Old Boys II | - | Independiente II | 2:1 | ||||
| 22. Round | 27/09/2022 | Independiente II | - | Arsenal de Sarandí II | 1:1 | ||||
| 23. Round | 05/10/2022 | Central Córdoba SdE II | - | Independiente II | 0:1 | ||||
| 24. Round | 10/10/2022 | Independiente II | - | Tigre II | 1:1 | ||||
| 25. Round | 13/10/2022 | Barracas Central II | - | Independiente II | 0:1 | ||||
| 26. Round | 17/10/2022 | Banfield II | - | Independiente II | 0:0 | ||||
| 27. Round | 21/10/2022 | Independiente II | - | Boca Juniors II | 0:3 |
Argentina