| 1. Round | 07/08/2010 | AJ Auxerre | - | FC Lorient | 2:2 | ||||
| 2. Round | 14/08/2010 | Stade Brestois 29 | - | AJ Auxerre | 1:1 |  |
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| 3. Round | 21/08/2010 | AJ Auxerre | - | Valenciennes FC | 1:1 | |
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| 4. Round | 29/08/2010 | AS Monaco | - | AJ Auxerre | 2:0 | ||||
| 5. Round | 11/09/2010 | AJ Auxerre | - | SM Caen | 1:1 | ||||
| 6. Round | 19/09/2010 | Lille OSC | - | AJ Auxerre | 1:0 | |
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| 7. Round | 25/09/2010 | AJ Auxerre | - | AS Nancy Lorraine | 2:2 | |
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| 10. Round | 24/10/2010 | Paris Saint-Germain | - | AJ Auxerre | 2:3 |  |
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| 11. Round | 30/10/2010 | AJ Auxerre | - | OGC Nice | 2:0 | ||||
| 12. Round | 06/11/2010 | FC Sochaux | - | AJ Auxerre | 1:1 | ||||
| 13. Round | 14/11/2010 | AJ Auxerre | - | Stade Rennais | 2:1 | ||||
| 14. Round | 20/11/2010 | AS Saint-Étienne | - | AJ Auxerre | 1:1 | |
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| 15. Round | 28/11/2010 | AJ Auxerre | - | Toulouse FC | 1:2 | |
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| 16. Round | 04/12/2010 | RC Lens | - | AJ Auxerre | 1:1 | |
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| 17. Round | 11/12/2010 | AJ Auxerre | - | Olympique Marseille | 1:1 | ||||
| 18. Round | 18/12/2010 | Montpellier HSC | - | AJ Auxerre | 1:1 | ||||
| 19. Round | 22/12/2010 | Olympique Lyonnais | - | AJ Auxerre | 1:1 | |
France
