| 1. Round | 22/08/2021 | AS Cannes [Youth] | - | AC Ajaccio [Youth] | 1:0 | ||||
| 3. Round | 05/09/2021 | Toulouse FC [Youth] | - | AC Ajaccio [Youth] | 4:2 | ||||
| 4. Round | 12/09/2021 | AC Ajaccio [Youth] | - | FC Istres [Youth] | 0:1 | ||||
| 5. Round | 19/09/2021 | Pieve di Lota [Youth] | - | AC Ajaccio [Youth] | 1:3 |  |
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| 6. Round | 25/09/2021 | AC Ajaccio [Youth] | - | AS Monaco [Youth] | 0:2 | ||||
| 7. Round | 03/10/2021 | US Colomiers [Youth] | - | AC Ajaccio [Youth] | 3:1 | ||||
| 8. Round | 10/10/2021 | AS Saint-Étienne [Youth] | - | AC Ajaccio [Youth] | 1:1 | ||||
| 9. Round | 17/10/2021 | AC Ajaccio [Youth] | - | Nîmes Olympique [Youth] | 3:0 | ||||
| 10. Round | 24/10/2021 | Montpellier HSC [Youth] | - | AC Ajaccio [Youth] | 2:2 | |
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| 11. Round | 13/11/2021 | AC Ajaccio [Youth] | - | AS Béziers [Youth] | 1:0 | ||||
| 14. Round | 05/12/2021 | OGC Nice [Youth] | - | AC Ajaccio [Youth] | 2:0 | ||||
| 17. Round | 06/02/2022 | AC Ajaccio [Youth] | - | Pieve di Lota [Youth] | 9:0 | ||||
| 23. Round | 10/04/2022 | AS Béziers [Youth] | - | AC Ajaccio [Youth] | 2:0 |
France