| 2. Round | 29/08/2020 | AS Nancy Lorraine | - | EA Guingamp | 2:2 | ||||
| 3. Round | 12/09/2020 | EA Guingamp | - | Havre AC | 1:3 |  |
|||
| 4. Round | 19/09/2020 | Pau FC | - | EA Guingamp | 0:1 | ||||
| 5. Round | 26/09/2020 | EA Guingamp | - | Grenoble Foot 38 | 1:0 | ||||
| 6. Round | 03/10/2020 | USL Dunkerque | - | EA Guingamp | 1:0 | ||||
| 7. Round | 19/10/2020 | EA Guingamp | - | AJ Auxerre | 2:0 | ||||
| 8. Round | 24/10/2020 | SM Caen | - | EA Guingamp | 1:0 | ||||
| 15. Round | 12/12/2020 | EA Guingamp | - | Valenciennes FC | 1:1 | ||||
| 16. Round | 18/12/2020 | FC Chambly | - | EA Guingamp | 3:0 | |
|||
| 17. Round | 22/12/2020 | Paris FC | - | EA Guingamp | 3:2 | |
|||
| 18. Round | 05/01/2021 | EA Guingamp | - | Amiens SC | 2:2 | ||||
| 19. Round | 08/01/2021 | LB Châteauroux | - | EA Guingamp | 2:3 | ||||
| 20. Round | 16/01/2021 | EA Guingamp | - | AS Nancy Lorraine | 0:0 | ||||
| 23. Round | 02/02/2021 | Grenoble Foot 38 | - | EA Guingamp | 2:1 | ||||
| 25. Round | 13/02/2021 | AJ Auxerre | - | EA Guingamp | 1:1 | ||||
| 26. Round | 22/02/2021 | EA Guingamp | - | SM Caen | 2:2 | ||||
| 27. Round | 27/02/2021 | FC Sochaux | - | EA Guingamp | 0:0 | ||||
| 28. Round | 02/03/2021 | EA Guingamp | - | Clermont Foot 63 | 0:5 | ||||
| 37. Round | 08/05/2021 | EA Guingamp | - | LB Châteauroux | 2:0 |
France
Martinique 
