| 1. Round | 18/08/1987 | Cercle Brugge | - | KV Mechelen | 0:0 | ||||
| 2. Round | 21/08/1987 | KV Mechelen | - | Standard Liège | 2:1 | ||||
| 3. Round | 25/08/1987 | Royal Antwerp FC | - | KV Mechelen | 3:0 |  |
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| 4. Round | 01/09/1987 | KV Mechelen | - | KV Kortrijk | 2:0 | ||||
| 5. Round | 05/09/1987 | Racing Jet de Bruxelles | - | KV Mechelen | 0:2 | ||||
| 8. Round | 25/09/1987 | Sporting Lokeren | - | KV Mechelen | 0:1 | ||||
| 9. Round | 03/10/1987 | KV Mechelen | - | Club Brugge KV | 2:4 | ||||
| 10. Round | 10/10/1987 | RFC Liège | - | KV Mechelen | 0:0 | ||||
| 22. Round | 19/02/1988 | KV Mechelen | - | Racing Jet Wavre | 2:0 | ||||
| 23. Round | 26/02/1988 | Sint-Truidense VV | - | KV Mechelen | 0:0 | ||||
| 26. Round | 19/03/1988 | Club Brugge KV | - | KV Mechelen | 2:1 |  |
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| 27. Round | 01/04/1988 | KV Mechelen | - | RFC Liège | 0:1 | ||||
| 28. Round | 08/04/1988 | K. Beerschot VAV | - | KV Mechelen | 0:1 | ||||
| 29. Round | 15/04/1988 | KV Mechelen | - | RWD Molenbeek | 3:0 | ||||
| 30. Round | 22/04/1988 | KFC Winterslag | - | KV Mechelen | 0:0 | ||||
| 31. Round | 29/04/1988 | KV Mechelen | - | KSV Waregem | 0:0 | ||||
| 32. Round | 06/05/1988 | KAA Gent | - | KV Mechelen | 1:1 |
Germany