| 5. Round | 25/08/2000 | OGC Nice | - | AS Nancy Lorraine | 2:1 | ||||
| 6. Round | 28/08/2000 | AS Nancy Lorraine | - | Nîmes Olympique | 3:1 | ||||
| 7. Round | 31/08/2000 | SM Caen | - | AS Nancy Lorraine | 0:3 |  |
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| 8. Round | 04/09/2000 | AS Nancy Lorraine | - | Chamois Niortais | 0:0 | ||||
| 9. Round | 08/09/2000 | AS Cannes | - | AS Nancy Lorraine | 0:2 |  |
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| 11. Round | 22/09/2000 | LB Châteauroux | - | AS Nancy Lorraine | 0:0 | ||||
| 12. Round | 29/09/2000 | AS Nancy Lorraine | - | Angers SCO | 0:0 | ||||
| 14. Round | 09/10/2000 | AS Nancy Lorraine | - | FC Sochaux | 1:2 | |
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| 15. Round | 14/10/2000 | Montpellier HSC | - | AS Nancy Lorraine | 1:1 | ||||
| 20. Round | 17/11/2000 | Stade Lavallois | - | AS Nancy Lorraine | 0:0 | ||||
| 21. Round | 28/11/2000 | AS Nancy Lorraine | - | US Créteil-Lusitanos | 2:0 | ||||
| 24. Round | 20/12/2000 | Nîmes Olympique | - | AS Nancy Lorraine | 1:2 | ||||
| 32. Round | 20/03/2001 | FC Sochaux | - | AS Nancy Lorraine | 1:1 |
France