| 2. Round | 14/08/2021 | AS Béziers | - | Trélissac FC | 2:0 |  |
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| 3. Round | 21/08/2021 | Moulins Yzeure Foot | - | AS Béziers | 0:0 | |
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| 4. Round | 27/08/2021 | Bergerac Périgord FC | - | AS Béziers | 2:0 | ||||
| 5. Round | 04/09/2021 | AS Béziers | - | Stade Montois | 3:2 | ||||
| 6. Round | 11/09/2021 | Bourges Foot 18 | - | AS Béziers | 0:1 | ||||
| 10. Round | 23/10/2021 | Montpellier HSC B | - | AS Béziers | 2:0 | ||||
| 15. Round | 29/01/2022 | AS Béziers | - | Canet Roussillon | 4:0 | ||||
| 17. Round | 05/02/2022 | AS Béziers | - | Moulins Yzeure Foot | 3:2 | ||||
| 18. Round | 12/02/2022 | AS Béziers | - | Bergerac Périgord FC | 1:1 | ||||
| 16. Round | 23/02/2022 | Trélissac FC | - | AS Béziers | 0:0 | ||||
| 21. Round | 12/03/2022 | Le Puy Foot 43 | - | AS Béziers | 2:0 | ||||
| 22. Round | 19/03/2022 | AS Béziers | - | Angers SCO B | 1:1 | |
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| 23. Round | 25/03/2022 | Vendée Les Herbiers | - | AS Béziers | 0:0 | |
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| 29. Round | 21/05/2022 | Canet Roussillon | - | AS Béziers | 4:1 | ||||
| 30. Round | 28/05/2022 | AS Béziers | - | Angoulême CFC | 3:1 |
France