| 5. Round | 26/09/2009 | Athletic Club | - | Sevilla FC | 0:4 | ||||
| 17. Round | 09/01/2010 | Sevilla FC | - | Racing Santander | 1:2 | ||||
| 18. Round | 16/01/2010 | FC Barcelona | - | Sevilla FC | 4:0 | ||||
| 21. Round | 07/02/2010 | Real Zaragoza | - | Sevilla FC | 2:1 | ||||
| 28. Round | 23/03/2010 | Sevilla FC | - | Xerez CD | 1:1 | ||||
| 29. Round | 28/03/2010 | Villarreal CF | - | Sevilla FC | 3:0 | ||||
| 30. Round | 03/04/2010 | Sevilla FC | - | CD Tenerife | 3:0 |  |
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| 31. Round | 10/04/2010 | Málaga CF | - | Sevilla FC | 1:2 | ||||
| 32. Round | 13/04/2010 | Real Valladolid | - | Sevilla FC | 2:1 | ||||
| 33. Round | 17/04/2010 | Sevilla FC | - | Sporting Gijón | 3:0 |
Spain