| 1. Round | 11/09/1960 | Real Sociedad | - | Granada CF | 1:0 | ||||
| 2. Round | 18/09/1960 | Granada CF | - | Elche CF | 1:1 | ||||
| 5. Round | 09/10/1960 | Sevilla FC | - | Granada CF | 0:0 | ||||
| 6. Round | 16/10/1960 | Granada CF | - | Athletic Club | 2:0 | ||||
| 7. Round | 23/10/1960 | Granada CF | - | Real Madrid | 2:3 | ||||
| 8. Round | 06/11/1960 | Real Zaragoza | - | Granada CF | 4:1 | ||||
| 9. Round | 13/11/1960 | Granada CF | - | RCD Mallorca | 4:0 | ||||
| 10. Round | 20/11/1960 | Real Oviedo | - | Granada CF | 0:0 | ||||
| 11. Round | 27/11/1960 | Granada CF | - | FC Barcelona | 1:1 | ||||
| 12. Round | 04/12/1960 | Real Valladolid | - | Granada CF | 4:0 | ||||
| 13. Round | 11/12/1960 | Granada CF | - | Real Betis | 1:2 | ||||
| 19. Round | 29/01/1961 | Valencia CF | - | Granada CF | 3:1 | ||||
| 20. Round | 05/02/1961 | Granada CF | - | Sevilla FC | 0:2 | ||||
| 21. Round | 12/02/1961 | Athletic Club | - | Granada CF | 3:0 | ||||
| 22. Round | 19/02/1961 | Real Madrid | - | Granada CF | 5:0 | ||||
| 23. Round | 26/02/1961 | Granada CF | - | Real Zaragoza | 2:3 | ||||
| 28. Round | 09/04/1961 | Real Betis | - | Granada CF | 2:1 | ||||
| 29. Round | 23/04/1961 | Granada CF | - | Racing Santander | 5:1 | ||||
| 30. Round | 30/04/1961 | Atlético Madrid | - | Granada CF | 4:0 |
Argentina