| 5. Round | 24/02/2011 | Deportes Iquique | - | Universidad de Concepción | 1:3 |  |
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| 6. Round | 27/02/2011 | Deportes Iquique | - | Ñublense | 2:1 |  |
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| 7. Round | 05/03/2011 | Huachipato | - | Deportes Iquique | 3:1 | ||||
| 8. Round | 13/03/2011 | Deportes Iquique | - | Santiago Wanderers | 4:1 | ||||
| 9. Round | 19/03/2011 | Unión Española | - | Deportes Iquique | 3:0 | ||||
| 10. Round | 02/04/2011 | La Serena | - | Deportes Iquique | 0:0 | ||||
| 11. Round | 10/04/2011 | Deportes Iquique | - | Universidad de Chile | 2:2 | ||||
| 12. Round | 16/04/2011 | Palestino | - | Deportes Iquique | 1:0 | ||||
| 13. Round | 24/04/2011 | Deportes Iquique | - | Audax Italiano | 2:0 | ||||
| 14. Round | 29/04/2011 | O'Higgins | - | Deportes Iquique | 0:1 | ||||
| 15. Round | 08/05/2011 | Deportes Iquique | - | Unión La Calera | 1:0 | |
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| 16. Round | 15/05/2011 | Colo-Colo | - | Deportes Iquique | 1:1 | ||||
| 17. Round | 22/05/2011 | Deportes Iquique | - | Cobresal | 1:1 | |
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Chile