| Recalificación | 09/05/2021 | Santos Laguna | - | Gallos Blancos | 5:0 |  |
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| Quarter-finals | 14/05/2021 | Santos Laguna | - | CF Monterrey | 2:1 | ||||
| Semi-finals | 21/05/2021 | Santos Laguna | - | Puebla FC | 3:0 | ||||
| Semi-finals | 24/05/2021 | Puebla FC | - | Santos Laguna | 1:0 | ||||
| Final | 28/05/2021 | Santos Laguna | - | Cruz Azul | 0:1 | ||||
| Final | 31/05/2021 | Cruz Azul | - | Santos Laguna | 1:1 |
Colombia