| 2. Round | 12/09/2021 | Valencia CF [Women] | - | Sporting de Huelva [Women] | 2:2 | ||||
| 3. Round | 25/09/2021 | FC Barcelona [Women] | - | Valencia CF [Women] | 8:0 | ||||
| 4. Round | 29/09/2021 | Valencia CF [Women] | - | Athletic Club [Women] | 1:3 | ||||
| 19. Round | 30/01/2022 | Valencia CF [Women] | - | UDG Tenerife Sur [Women] | 1:2 | ||||
| 20. Round | 02/02/2022 | Rayo Vallecano [Women] | - | Valencia CF [Women] | 1:1 | ||||
| 21. Round | 06/02/2022 | Valencia CF [Women] | - | Levante UD [Women] | 2:0 |  |
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| 22. Round | 13/02/2022 | Valencia CF [Women] | - | CD Alavés [Women] | 1:0 | ||||
| 23. Round | 06/03/2022 | Madrid CFF [Women] | - | Valencia CF [Women] | 1:0 | ||||
| 25. Round | 26/03/2022 | Atlético Madrid [Women] | - | Valencia CF [Women] | 3:0 | ||||
| 24. Round | 30/03/2022 | Valencia CF [Women] | - | Villarreal CF [Women] | 2:1 | ||||
| 26. Round | 02/04/2022 | Athletic Club [Women] | - | Valencia CF [Women] | 2:2 | ||||
| 30. Round | 15/05/2022 | SD Eibar [Women] | - | Valencia CF [Women] | 5:1 |
Spain