| 6. Round | 29/09/2024 | DOMTAC FC [Youth B] | - | FC Istres [Youth B] | 0:2 | ||||
| 7. Round | 06/10/2024 | FC Istres [Youth B] | - | FC Marmande 47 [Youth B] | 4:2 | ||||
| 8. Round | 12/10/2024 | Toulouse FC [Youth B] | - | FC Istres [Youth B] | 0:1 | ||||
| 9. Round | 20/10/2024 | FC Istres [Youth B] | - | SA Mérignac [Youth B] | 3:1 |  |
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| 10. Round | 02/11/2024 | Montpellier HSC [Youth B] | - | FC Istres [Youth B] | 0:1 | ||||
| 11. Round | 10/11/2024 | FC Istres [Youth B] | - | Jeunesse Villenavaise [Youth B] | 2:1 | ||||
| 12. Round | 17/11/2024 | Olympique Rovenain [Youth B] | - | FC Istres [Youth B] | 1:3 | ||||
| 13. Round | 24/11/2024 | FC Istres [Youth B] | - | AS Béziers [Youth B] | 1:4 | ||||
| 14. Round | 01/12/2024 | UJS Toulouse [Youth B] | - | FC Istres [Youth B] | 1:0 | ||||
| 15. Round | 08/12/2024 | FC Istres [Youth B] | - | Castelnau Le Crès FC [Youth B] | 4:1 | ||||
| 19. Round | 16/02/2025 | FC Marmande 47 [Youth B] | - | FC Istres [Youth B] | 1:0 | ||||
| 20. Round | 09/03/2025 | FC Istres [Youth B] | - | Toulouse FC [Youth B] | 2:2 | ||||
| 21. Round | 16/03/2025 | SA Mérignac [Youth B] | - | FC Istres [Youth B] | 2:5 | ||||
| 22. Round | 23/03/2025 | FC Istres [Youth B] | - | Montpellier HSC [Youth B] | 1:1 | |
France