| 3. Round | 11/09/2021 | Stade Rennais [Youth B] | - | SO Cholet [Youth B] | 5:5 | ||||
| 7. Round | 10/10/2021 | Chamois Niortais [Youth B] | - | Stade Rennais [Youth B] | 0:0 | ||||
| 8. Round | 16/10/2021 | Stade Rennais [Youth B] | - | EA Guingamp [Youth B] | 2:0 | ||||
| 9. Round | 23/10/2021 | La Roche VF [Youth B] | - | Stade Rennais [Youth B] | 1:1 | ||||
| 10. Round | 13/11/2021 | Stade Rennais [Youth B] | - | CPBB Rennes [Youth B] | 1:1 | ||||
| 11. Round | 21/11/2021 | Angoulême CFC [Youth B] | - | Stade Rennais [Youth B] | 0:2 | ||||
| 12. Round | 27/11/2021 | Stade Rennais [Youth B] | - | Vannes OC [Youth B] | 2:0 | ||||
| 13. Round | 04/12/2021 | FC Nantes [Youth B] | - | Stade Rennais [Youth B] | 1:2 | ||||
| 16. Round | 05/02/2022 | Stade Rennais [Youth B] | - | FC Lorient [Youth B] | 2:1 | ||||
| 18. Round | 05/03/2022 | Stade brestois 29 [Youth B] | - | Stade Rennais [Youth B] | 3:2 | ||||
| 21. Round | 26/03/2022 | Stade Rennais [Youth B] | - | La Roche VF [Youth B] | 5:0 | ||||
| 19. Round | 30/03/2022 | Stade Rennais [Youth B] | - | Chamois Niortais [Youth B] | 0:3 | ||||
| 22. Round | 02/04/2022 | CPBB Rennes [Youth B] | - | Stade Rennais [Youth B] | 3:1 |
France