| 1. Round | 07/08/2021 | FC Lorient B | - | AS Vitré | 1:0 | ||||
| 2. Round | 14/08/2021 | AS Vitré | - | EA Guingamp B | 0:4 | ||||
| 3. Round | 21/08/2021 | AS Poissy | - | AS Vitré | 3:0 | ||||
| 4. Round | 28/08/2021 | AS Vitré | - | C'Chartres Football | 0:1 | ||||
| 5. Round | 04/09/2021 | Châteaubriant Voltigeurs | - | AS Vitré | 1:0 | ||||
| 19. Round | 19/02/2022 | AS Vitré | - | Châteaubriant Voltigeurs | 2:0 | ||||
| 20. Round | 05/03/2022 | Vannes OC | - | AS Vitré | 3:1 | ||||
| 21. Round | 12/03/2022 | AS Vitré | - | US Granvillaise | 1:1 | ||||
| 22. Round | 19/03/2022 | SO Romorantin | - | AS Vitré | 1:1 | ||||
| 23. Round | 26/03/2022 | AS Vitré | - | FC Rouen 1899 | 2:2 |
France