| 1. Round | 12/02/2022 | Banfield II | - | San Lorenzo II | 2:1 | ||||
| 2. Round | 16/02/2022 | Sarmiento de Junín II | - | Banfield II | 0:1 | ||||
| 9. Round | 08/04/2022 | Patronato de Paraná II | - | Banfield II | 0:2 | ||||
| 10. Round | 14/04/2022 | Banfield II | - | River Plate II | 2:3 | ||||
| 12. Round | 26/04/2022 | Banfield II | - | Talleres de Córdoba II | 0:0 | ||||
| 14. Round | 06/05/2022 | Banfield II | - | Atlético Tucumán II | 3:4 |
Argentina