| 1. Round | 11/02/2022 | Newell's Old Boys | - | Defensa y Justicia | 1:0 | ||||
| 2. Round | 15/02/2022 | Argentinos Juniors | - | Newell's Old Boys | 3:0 | ||||
| 3. Round | 21/02/2022 | Newell's Old Boys | - | River Plate | 0:2 | ||||
| 11. Round | 20/04/2022 | Newell's Old Boys | - | Banfield | 1:0 |  |
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| 12. Round | 24/04/2022 | Racing Club | - | Newell's Old Boys | 0:0 | ||||
| 13. Round | 28/04/2022 | Newell's Old Boys | - | San Lorenzo | 1:2 |
Argentina
Italy