| 4. Round | 28/08/2021 | Angers SCO B | - | Canet Roussillon | 2:0 | ||||
| 5. Round | 03/09/2021 | Angoulême CFC | - | Angers SCO B | 4:0 | ||||
| 7. Round | 18/09/2021 | Moulins Yzeure Foot | - | Angers SCO B | 0:0 | ||||
| 9. Round | 09/10/2021 | Stade Montois | - | Angers SCO B | 0:4 | ||||
| 11. Round | 06/11/2021 | Le Puy Foot 43 | - | Angers SCO B | 1:0 | ||||
| 12. Round | 20/11/2021 | Bergerac Périgord FC | - | Angers SCO B | 2:1 | ||||
| 15. Round | 15/01/2022 | Angers SCO B | - | FC Chamalières | 1:1 | ||||
| 16. Round | 22/01/2022 | US Colomiers | - | Angers SCO B | 0:0 | ||||
| 17. Round | 05/02/2022 | Angers SCO B | - | FC Nantes B | 1:0 | ||||
| 18. Round | 12/02/2022 | Canet Roussillon | - | Angers SCO B | 2:0 | ||||
| 24. Round | 09/04/2022 | Bourges Foot 18 | - | Angers SCO B | 0:1 | ||||
| 25. Round | 16/04/2022 | Angers SCO B | - | Le Puy Foot 43 | 0:2 | ||||
| 26. Round | 23/04/2022 | Angers SCO B | - | Bergerac Périgord FC | 0:1 | ||||
| 27. Round | 29/04/2022 | Vendée Les Herbiers | - | Angers SCO B | 1:1 |  |
|||
| 28. Round | 14/05/2022 | Angers SCO B | - | Montpellier HSC B | 1:0 |  |
France
Madagascar