| 1. Round | 29/08/2021 | FC Mantois [Youth B] | - | Tours FC [Youth B] | 2:0 | ||||
| 6. Round | 03/10/2021 | Tours FC [Youth B] | - | SM Caen [Youth B] | 2:1 | ||||
| 7. Round | 10/10/2021 | AS Vitré [Youth B] | - | Tours FC [Youth B] | 3:1 | ||||
| 10. Round | 14/11/2021 | Tours FC [Youth B] | - | Paris FC [Youth B] | 0:4 | ||||
| 17. Round | 12/02/2022 | Tours FC [Youth B] | - | Le Mans FC [Youth B] | 1:4 | ||||
| 18. Round | 06/03/2022 | SM Caen [Youth B] | - | Tours FC [Youth B] | 3:2 | ||||
| 19. Round | 13/03/2022 | Tours FC [Youth B] | - | AS Vitré [Youth B] | 2:1 | ||||
| 20. Round | 20/03/2022 | FC Rouen 1899 [Youth B] | - | Tours FC [Youth B] | 2:1 | ||||
| 22. Round | 03/04/2022 | Paris FC [Youth B] | - | Tours FC [Youth B] | 4:0 | ||||
| 23. Round | 09/04/2022 | Tours FC [Youth B] | - | US Orléans [Youth B] | 1:1 | ||||
| 24. Round | 14/04/2022 | Tours FC [Youth B] | - | US Avranches [Youth B] | 2:3 |
France