| 1. Round | 29/08/2021 | Entente Feignies Aulnoye [Youth B] | - | RC Lens [Youth B] | 1:3 | ||||
| 2. Round | 05/09/2021 | RC Lens [Youth B] | - | Paris 13 Atletico [Youth B] | 3:3 | ||||
| 3. Round | 11/09/2021 | JA Drancy [Youth B] | - | RC Lens [Youth B] | 0:5 | ||||
| 4. Round | 18/09/2021 | RC Lens [Youth B] | - | ESTAC Troyes [Youth B] | 4:0 | ||||
| 5. Round | 26/09/2021 | AC Boulogne-Billancourt [Youth B] | - | RC Lens [Youth B] | 2:1 | ||||
| 12. Round | 27/11/2021 | Stade de Reims [Youth B] | - | RC Lens [Youth B] | 1:1 | ||||
| 15. Round | 30/01/2022 | RC Lens [Youth B] | - | JA Drancy [Youth B] | 1:0 | ||||
| 16. Round | 05/02/2022 | ESTAC Troyes [Youth B] | - | RC Lens [Youth B] | 1:0 | ||||
| 18. Round | 06/03/2022 | Amiens SC [Youth B] | - | RC Lens [Youth B] | 5:0 | ||||
| 22. Round | 03/04/2022 | US Torcy [Youth B] | - | RC Lens [Youth B] | 1:1 | ||||
| 23. Round | 10/04/2022 | RC Lens [Youth B] | - | Montfermeil FC [Youth B] | 1:1 | ||||
| 26. Round | 15/05/2022 | RC Lens [Youth B] | - | Entente Feignies Aulnoye [Youth B] | 3:0 |
France