| 10. Round | 23/10/2010 | AS Saint-Étienne | - | SM Caen | 1:1 | ||||
| 11. Round | 30/10/2010 | Stade Brestois 29 | - | AS Saint-Étienne | 2:0 | ||||
| 12. Round | 06/11/2010 | AS Saint-Étienne | - | FC Lorient | 1:2 | ||||
| 16. Round | 05/12/2010 | AS Saint-Étienne | - | Girondins Bordeaux | 2:2 | ||||
| 17. Round | 12/12/2010 | AS Monaco | - | AS Saint-Étienne | 0:2 | ||||
| 18. Round | 18/12/2010 | AS Saint-Étienne | - | AC Arles-Avignon | 2:0 | ||||
| 19. Round | 22/12/2010 | Lille OSC | - | AS Saint-Étienne | 1:1 |  |
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| 20. Round | 15/01/2011 | RC Lens | - | AS Saint-Étienne | 2:1 | ||||
| 21. Round | 29/01/2011 | AS Saint-Étienne | - | Toulouse FC | 2:1 | ||||
| 22. Round | 05/02/2011 | Montpellier HSC | - | AS Saint-Étienne | 1:2 | |
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| 23. Round | 12/02/2011 | AS Saint-Étienne | - | Olympique Lyonnais | 1:4 | ||||
| 29. Round | 03/04/2011 | AS Saint-Étienne | - | Valenciennes FC | 1:1 | ||||
| 37. Round | 21/05/2011 | FC Sochaux | - | AS Saint-Étienne | 2:1 | ||||
| 38. Round | 29/05/2011 | AS Saint-Étienne | - | Paris Saint-Germain | 1:1 |
France