| 1. Round | 11/02/2022 | Central Córdoba SdE II | - | Barracas Central II | 5:1 |  |
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| 2. Round | 15/02/2022 | Tigre II | - | Central Córdoba SdE II | 1:1 | ||||
| 3. Round | 20/02/2022 | Central Córdoba SdE II | - | Colón de Santa Fe II | 2:0 | ||||
| 4. Round | 26/02/2022 | Aldosivi II | - | Central Córdoba SdE II | 0:1 | ||||
| 5. Round | 04/03/2022 | Central Córdoba SdE II | - | Rosario Central II | 0:3 | ||||
| 8. Round | 31/03/2022 | Central Córdoba SdE II | - | Huracán II | 1:0 | ||||
| 9. Round | 08/04/2022 | Estudiantes II | - | Central Córdoba SdE II | 0:0 | ||||
| 10. Round | 13/04/2022 | Central Córdoba SdE II | - | Arsenal de Sarandí II | 2:0 | |
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| 11. Round | 19/04/2022 | Vélez Sarsfield II | - | Central Córdoba SdE II | 1:0 | ||||
| 13. Round | 02/05/2022 | Godoy Cruz II | - | Central Córdoba SdE II | 1:0 | ||||
| 14. Round | 06/05/2022 | Central Córdoba SdE II | - | Lanús II | 2:2 |
Argentina