| 1. Round | 29/08/2021 | Stade Rennais [Youth B] | - | Angers SCO [Youth B] | 1:3 | ||||
| 2. Round | 05/09/2021 | Angers SCO [Youth B] | - | Stade brestois 29 [Youth B] | 2:1 | ||||
| 3. Round | 12/09/2021 | Chamois Niortais [Youth B] | - | Angers SCO [Youth B] | 2:1 | ||||
| 4. Round | 19/09/2021 | Angers SCO [Youth B] | - | EA Guingamp [Youth B] | 7:0 | ||||
| 11. Round | 21/11/2021 | Angers SCO [Youth B] | - | LB Châteauroux [Youth B] | 4:2 | ||||
| 12. Round | 28/11/2021 | SO Cholet [Youth B] | - | Angers SCO [Youth B] | 2:4 | ||||
| 16. Round | 06/02/2022 | EA Guingamp [Youth B] | - | Angers SCO [Youth B] | 3:4 | ||||
| 23. Round | 10/04/2022 | LB Châteauroux [Youth B] | - | Angers SCO [Youth B] | 1:3 | ||||
| 24. Round | 17/04/2022 | Angers SCO [Youth B] | - | SO Cholet [Youth B] | 5:2 |
France