| 1. Round | 06/08/2021 | FC Sète | - | FC Bastia-Borgo | 2:0 | ||||
| 2. Round | 13/08/2021 | FC Bastia-Borgo | - | FC Bourg-Péronnas | 2:2 |  |
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| 3. Round | 20/08/2021 | CS Sedan | - | FC Bastia-Borgo | 1:0 | ||||
| 4. Round | 27/08/2021 | FC Bastia-Borgo | - | Stade Lavallois | 2:2 | ||||
| 5. Round | 03/09/2021 | US Concarneau | - | FC Bastia-Borgo | 2:1 | |
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| 6. Round | 10/09/2021 | FC Bastia-Borgo | - | US Boulogne | 0:3 | |
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| 7. Round | 17/09/2021 | FC Chambly | - | FC Bastia-Borgo | 2:2 | ||||
| 9. Round | 01/10/2021 | US Orléans | - | FC Bastia-Borgo | 4:0 | ||||
| 10. Round | 08/10/2021 | FC Bastia-Borgo | - | FC Annecy | 1:2 | ||||
| 11. Round | 22/10/2021 | FC Villefranche Beaujolais | - | FC Bastia-Borgo | 1:1 |  |
France