| 2. Round | 15/02/2022 | Rosario Central II | - | Vélez Sarsfield II | 1:1 | ||||
| 5. Round | 05/03/2022 | Vélez Sarsfield II | - | Estudiantes II | 0:2 |  |
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| 8. Round | 31/03/2022 | Vélez Sarsfield II | - | Lanús II | 2:3 | ||||
| 10. Round | 13/04/2022 | Godoy Cruz II | - | Vélez Sarsfield II | 1:0 | ||||
| 11. Round | 19/04/2022 | Vélez Sarsfield II | - | Central Córdoba SdE II | 1:0 | ||||
| 12. Round | 24/04/2022 | Barracas Central II | - | Vélez Sarsfield II | 0:0 | ||||
| 14. Round | 06/05/2022 | Colón de Santa Fe II | - | Vélez Sarsfield II | 1:0 |
Argentina