| 7. Round | 11/07/2022 | Defensa y Justicia | - | Aldosivi | 3:2 | ||||
| 10. Round | 25/07/2022 | Newell's Old Boys | - | Defensa y Justicia | 1:2 |  |
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| 14. Round | 18/08/2022 | Barracas Central | - | Defensa y Justicia | 3:1 | ||||
| 15. Round | 22/08/2022 | Defensa y Justicia | - | Boca Juniors | 0:1 | ||||
| 16. Round | 27/08/2022 | Banfield | - | Defensa y Justicia | 1:2 | ||||
| 17. Round | 05/09/2022 | Defensa y Justicia | - | San Lorenzo | 0:0 | ||||
| 18. Round | 12/09/2022 | Talleres de Córdoba | - | Defensa y Justicia | 1:0 | ||||
| 19. Round | 15/09/2022 | Defensa y Justicia | - | Argentinos Juniors | 2:1 | ||||
| 20. Round | 20/09/2022 | Estudiantes | - | Defensa y Justicia | 1:2 | ||||
| 22. Round | 01/10/2022 | Platense | - | Defensa y Justicia | 0:0 | ||||
| 23. Round | 05/10/2022 | Defensa y Justicia | - | Racing Club | 3:3 | ||||
| 24. Round | 10/10/2022 | Rosario Central | - | Defensa y Justicia | 0:0 | ||||
| 25. Round | 14/10/2022 | Defensa y Justicia | - | Unión de Santa Fe | 1:0 | ||||
| 26. Round | 18/10/2022 | Colón de Santa Fe | - | Defensa y Justicia | 1:2 |
Argentina
Italy