| 2. Round | 14/08/2021 | AS Monaco B | - | RC Grasse | 0:1 |  |
|||
| 3. Round | 21/08/2021 | Louhans-Cuiseaux | - | AS Monaco B | 1:1 | ||||
| 4. Round | 28/08/2021 | AS Monaco B | - | Hyères FC | 0:1 | ||||
| 5. Round | 04/09/2021 | Lyon-La Duchère | - | AS Monaco B | 0:2 | |
|||
| 6. Round | 11/09/2021 | SC Toulon | - | AS Monaco B | 3:0 | ||||
| 7. Round | 18/09/2021 | AS Monaco B | - | FC Martigues | 2:0 |  |
|||
| 9. Round | 09/10/2021 | AS Monaco B | - | AS Saint-Priest | 4:2 | |
|||
| 10. Round | 23/10/2021 | Étoile FC | - | AS Monaco B | 1:1 | |
|||
| 12. Round | 20/11/2021 | Aubagne FC | - | AS Monaco B | 4:1 | |
|||
| 13. Round | 04/12/2021 | AS Monaco B | - | Jura Sud | 1:1 | ||||
| 14. Round | 11/12/2021 | Olympique Marseille B | - | AS Monaco B | 0:1 |
France
