| 3. Round | 19/09/2021 | Espanyol Barcelona B | - | CF Badalona | 1:0 | ||||
| 4. Round | 26/09/2021 | CE Europa | - | Espanyol Barcelona B | 1:3 | ||||
| 6. Round | 10/10/2021 | CD Ibiza | - | Espanyol Barcelona B | 2:1 | ||||
| 7. Round | 17/10/2021 | Espanyol Barcelona B | - | SD Tarazona | 1:1 | ||||
| 8. Round | 24/10/2021 | CD Teruel | - | Espanyol Barcelona B | 3:2 | ||||
| 9. Round | 30/10/2021 | Espanyol Barcelona B | - | CD Ebro | 3:0 | ||||
| 11. Round | 14/11/2021 | SD Formentera | - | Espanyol Barcelona B | 0:1 | ||||
| 12. Round | 21/11/2021 | Espanyol Barcelona B | - | Cerdanyola FC | 2:1 | ||||
| 15. Round | 12/12/2021 | SD Ejea | - | Espanyol Barcelona B | 1:4 |
Spain