| 4. Round | 20/06/2022 | Argentinos Juniors II | - | Newell's Old Boys II | 1:0 | ||||
| 5. Round | 25/06/2022 | Newell's Old Boys II | - | Estudiantes II | 0:0 | ||||
| 7. Round | 09/07/2022 | Newell's Old Boys II | - | Platense II | 3:0 | ||||
| 8. Round | 14/07/2022 | Racing Club II | - | Newell's Old Boys II | 4:4 | ||||
| 9. Round | 18/07/2022 | Newell's Old Boys II | - | Rosario Central II | 2:1 | ||||
| 10. Round | 24/07/2022 | Defensa y Justicia II | - | Newell's Old Boys II | 1:2 | ||||
| 12. Round | 06/08/2022 | Colón de Santa Fe II | - | Newell's Old Boys II | 0:2 |  |
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| 13. Round | 11/08/2022 | Newell's Old Boys II | - | River Plate II | 2:0 | ||||
| 14. Round | 15/08/2022 | Lanús II | - | Newell's Old Boys II | 2:0 | ||||
| 15. Round | 21/08/2022 | Newell's Old Boys II | - | Huracán II | 2:1 | ||||
| 16. Round | 26/08/2022 | Godoy Cruz II | - | Newell's Old Boys II | 1:1 | ||||
| 17. Round | 31/08/2022 | Newell's Old Boys II | - | Vélez Sarsfield II | 0:2 |
Argentina