| 1. Round | 27/08/2017 | San Lorenzo | - | Racing Club | 1:1 | ||||
| 9. Round | 18/11/2017 | San Martín de San Juan | - | San Lorenzo | 1:3 |  |
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| 12. Round | 30/11/2017 | San Lorenzo | - | Atlético Tucumán | 2:0 | ||||
| 11. Round | 03/12/2017 | Tigre | - | San Lorenzo | 1:2 | ||||
| 16. Round | 17/02/2018 | San Lorenzo | - | Newell's Old Boys | 1:0 | ||||
| 17. Round | 27/02/2018 | Gimnasia de La Plata | - | San Lorenzo | 1:0 | ||||
| 18. Round | 03/03/2018 | San Lorenzo | - | Unión de Santa Fe | 0:0 | ||||
| 21. Round | 02/04/2018 | Lanús | - | San Lorenzo | 0:2 | |
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| 22. Round | 08/04/2018 | San Lorenzo | - | Godoy Cruz | 0:5 | ||||
| 25. Round | 29/04/2018 | Patronato de Paraná | - | San Lorenzo | 0:0 | ||||
| 26. Round | 05/05/2018 | San Lorenzo | - | Belgrano de Córdoba | 2:0 |
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