| 1. Round | 17/07/2021 | Proleter Novi Sad | - | Partizan | 0:4 | ||||
| 2. Round | 25/07/2021 | Vojvodina | - | Partizan | 0:2 | ||||
| 3. Round | 01/08/2021 | Partizan | - | FK Voždovac | 4:0 | ||||
| 4. Round | 08/08/2021 | FK Novi Pazar | - | Partizan | 1:4 | ||||
| 17. Round | 21/11/2021 | Partizan | - | Vojvodina | 4:1 | ||||
| 19. Round | 05/12/2021 | Partizan | - | FK Novi Pazar | 2:0 |  |
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| 20. Round | 15/12/2021 | FK Metalac | - | Partizan | 0:3 | ||||
| 21. Round | 18/12/2021 | Partizan | - | FK Kolubara | 1:0 | ||||
| 23. Round | 20/02/2022 | Partizan | - | FK Radnički 1923 | 2:0 | ||||
| 24. Round | 27/02/2022 | Crvena Zvezda | - | Partizan | 2:0 | ||||
| 25. Round | 03/03/2022 | Partizan | - | Mladost Lučani | 2:1 | ||||
| 26. Round | 06/03/2022 | Spartak Subotica | - | Partizan | 0:1 | ||||
| 27. Round | 13/03/2022 | Partizan | - | FK Napredak | 0:0 | ||||
| 29. Round | 02/04/2022 | Partizan | - | TSC Bačka Topola | 2:0 |
Serbia