| 5. Round | 24/09/2021 | Racing Santander | - | Inter de Madrid | 2:0 | ||||
| 7. Round | 09/10/2021 | Racing Santander | - | CD Calahorra | 1:0 | ||||
| 8. Round | 17/10/2021 | CD Badajoz | - | Racing Santander | 0:1 | ||||
| 10. Round | 31/10/2021 | Real Unión | - | Racing Santander | 1:2 | ||||
| 11. Round | 07/11/2021 | Cultural Leonesa | - | Racing Santander | 3:0 | ||||
| 13. Round | 21/11/2021 | Zamora CF | - | Racing Santander | 0:3 | ||||
| 17. Round | 18/12/2021 | Extremadura UD | - | Racing Santander | 2:4 |
Spain