| 6. Round | 19/09/2009 | OGC Nice | - | AS Monaco | 1:3 | ||||
| 7. Round | 26/09/2009 | AS Monaco | - | AS Saint-Étienne | 1:2 | ||||
| 8. Round | 04/10/2009 | Olympique Marseille | - | AS Monaco | 1:2 | ||||
| 9. Round | 18/10/2009 | AS Monaco | - | RC Lens | 2:0 | ||||
| 10. Round | 24/10/2009 | US Boulogne | - | AS Monaco | 1:3 | ||||
| 12. Round | 31/10/2009 | Girondins Bordeaux | - | AS Monaco | 1:0 |  |
|||
| 13. Round | 07/11/2009 | AS Monaco | - | Grenoble Foot 38 | 0:0 | ||||
| 14. Round | 21/11/2009 | AJ Auxerre | - | AS Monaco | 2:0 | ||||
| 16. Round | 05/12/2009 | Valenciennes FC | - | AS Monaco | 3:1 | ||||
| 24. Round | 13/02/2010 | AS Monaco | - | Olympique Marseille | 1:2 | ||||
| 26. Round | 27/02/2010 | AS Monaco | - | US Boulogne | 1:0 | ||||
| 27. Round | 06/03/2010 | Stade Rennais | - | AS Monaco | 1:0 | ||||
| 28. Round | 13/03/2010 | AS Monaco | - | Girondins Bordeaux | 0:0 | ||||
| 29. Round | 20/03/2010 | Grenoble Foot 38 | - | AS Monaco | 0:0 | ||||
| 31. Round | 03/04/2010 | Montpellier HSC | - | AS Monaco | 0:0 | ||||
| 33. Round | 18/04/2010 | Lille OSC | - | AS Monaco | 4:0 | ||||
| 35. Round | 27/04/2010 | AS Monaco | - | Le Mans UC 72 | 1:1 | ||||
| 34. Round | 12/05/2010 | Olympique Lyonnais | - | AS Monaco | 3:0 | ||||
| 38. Round | 15/05/2010 | Toulouse FC | - | AS Monaco | 0:0 |
France