| 1. Round | 07/08/2004 | Lille OSC | - | AJ Auxerre | 2:0 | ||||
| 10. Round | 16/10/2004 | Lille OSC | - | SC Bastia | 2:1 | ||||
| 11. Round | 24/10/2004 | Toulouse FC | - | Lille OSC | 1:0 |  |
|||
| 12. Round | 30/10/2004 | Lille OSC | - | AS Saint-Étienne | 1:0 | ||||
| 13. Round | 07/11/2004 | FC Istres | - | Lille OSC | 0:2 | |
|||
| 15. Round | 20/11/2004 | RC Lens | - | Lille OSC | 1:1 | ||||
| 19. Round | 18/12/2004 | AC Ajaccio | - | Lille OSC | 0:0 | ||||
| 21. Round | 15/01/2005 | Girondins Bordeaux | - | Lille OSC | 1:3 |  |
|||
| 22. Round | 23/01/2005 | Lille OSC | - | Olympique Lyonnais | 2:1 | ||||
| 23. Round | 26/01/2005 | OGC Nice | - | Lille OSC | 1:1 | ||||
| 25. Round | 05/02/2005 | Lille OSC | - | FC Sochaux | 0:0 | ||||
| 28. Round | 05/03/2005 | SC Bastia | - | Lille OSC | 3:1 | |
|
||
| 29. Round | 13/03/2005 | Lille OSC | - | Toulouse FC | 1:1 | ||||
| 30. Round | 20/03/2005 | AS Saint-Étienne | - | Lille OSC | 0:0 | ||||
| 33. Round | 16/04/2005 | Lille OSC | - | RC Lens | 2:1 | ||||
| 35. Round | 07/05/2005 | Lille OSC | - | Paris Saint-Germain | 1:0 | ||||
| 36. Round | 14/05/2005 | FC Nantes | - | Lille OSC | 1:3 | |
|||
| 37. Round | 21/05/2005 | Lille OSC | - | AC Ajaccio | 0:2 | ||||
| 38. Round | 28/05/2005 | AJ Auxerre | - | Lille OSC | 1:3 |
France
