| 1. Round | 04/08/2007 | Lille OSC | - | FC Lorient | 0:0 | ||||
| 2. Round | 12/08/2007 | FC Metz | - | Lille OSC | 1:2 | ||||
| 3. Round | 15/08/2007 | Lille OSC | - | FC Sochaux | 1:1 | ||||
| 10. Round | 06/10/2007 | Lille OSC | - | Valenciennes FC | 3:0 | ||||
| 11. Round | 20/10/2007 | SM Caen | - | Lille OSC | 1:0 | ||||
| 12. Round | 27/10/2007 | Lille OSC | - | RC Strasbourg | 0:3 | ||||
| 13. Round | 03/11/2007 | AJ Auxerre | - | Lille OSC | 0:1 | ||||
| 15. Round | 24/11/2007 | AS Nancy Lorraine | - | Lille OSC | 2:0 |  |
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| 18. Round | 15/12/2007 | Lille OSC | - | AS Saint-Étienne | 3:0 | ||||
| 20. Round | 12/01/2008 | Lille OSC | - | FC Metz | 1:1 | ||||
| 21. Round | 19/01/2008 | FC Sochaux | - | Lille OSC | 1:1 |  |
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| 23. Round | 26/01/2008 | Lille OSC | - | Paris Saint-Germain | 0:0 | ||||
| 19. Round | 11/03/2008 | RC Lens | - | Lille OSC | 1:2 | ||||
| 30. Round | 22/03/2008 | RC Strasbourg | - | Lille OSC | 0:1 | ||||
| 32. Round | 05/04/2008 | OGC Nice | - | Lille OSC | 0:0 | ||||
| 34. Round | 20/04/2008 | Olympique Marseille | - | Lille OSC | 1:3 |
France
