| 3. Round | 05/09/2021 | Paris Saint-Germain [Youth] | - | US Orléans [Youth] | 5:2 | ||||
| 4. Round | 12/09/2021 | US Orléans [Youth] | - | Havre AC [Youth] | 1:1 | ||||
| 11. Round | 14/11/2021 | US Orléans [Youth] | - | St-Pryvé St-Hilaire [Youth] | 2:1 | ||||
| 12. Round | 20/11/2021 | Lille OSC [Youth] | - | US Orléans [Youth] | 1:4 | ||||
| 20. Round | 20/03/2022 | US Orléans [Youth] | - | Évreux FC 27 [Youth] | 9:0 | ||||
| 21. Round | 26/03/2022 | RC Lens [Youth] | - | US Orléans [Youth] | 0:1 | ||||
| 24. Round | 17/04/2022 | US Orléans [Youth] | - | Lille OSC [Youth] | 4:2 | ||||
| 25. Round | 01/05/2022 | Entente Feignies Aulnoye [Youth] | - | US Orléans [Youth] | 1:1 |
France