| 2. Round | 05/09/2021 | Olympique de Valence [Youth B] | - | Clermont Foot 63 [Youth B] | 0:2 | ||||
| 5. Round | 25/09/2021 | Clermont Foot 63 [Youth B] | - | Lyon-La Duchère [Youth B] | 6:1 | ||||
| 6. Round | 03/10/2021 | AS Saint-Étienne [Youth B] | - | Clermont Foot 63 [Youth B] | 2:2 | ||||
| 7. Round | 10/10/2021 | Clermont Foot 63 [Youth B] | - | AS Saint-Priest [Youth B] | 1:2 | ||||
| 12. Round | 28/11/2021 | Clermont Foot 63 [Youth B] | - | Gazélec FC Ajaccio [Youth B] | 0:1 | ||||
| 14. Round | 16/01/2022 | Clermont Foot 63 [Youth B] | - | Olympique de Valence [Youth B] | 2:4 | ||||
| 15. Round | 26/02/2022 | AC Ajaccio [Youth B] | - | Clermont Foot 63 [Youth B] | 2:0 | ||||
| 18. Round | 06/03/2022 | Clermont Foot 63 [Youth B] | - | AS Saint-Étienne [Youth B] | 1:4 | ||||
| 23. Round | 10/04/2022 | Clermont Foot 63 [Youth B] | - | AS Monaco [Youth B] | 1:0 | ||||
| 25. Round | 01/05/2022 | Clermont Foot 63 [Youth B] | - | Andrézieux-Bouthéon FC [Youth B] | 3:2 | ||||
| 26. Round | 15/05/2022 | Olympique Marseille [Youth B] | - | Clermont Foot 63 [Youth B] | 3:1 |
France