| 2. Round | 28/07/1980 | AS Saint-Étienne | - | OGC Nice | 3:2 | ||||
| 13. Round | 04/10/1980 | Olympique Lyonnais | - | OGC Nice | 5:1 | ||||
| 18. Round | 11/11/1980 | OGC Nice | - | US Valenciennes-Anzin | 4:0 |  |
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| 19. Round | 22/11/1980 | AS Monaco | - | OGC Nice | 1:0 | ||||
| 20. Round | 28/11/1980 | OGC Nice | - | AS Saint-Étienne | 0:1 | ||||
| 21. Round | 05/12/1980 | FC Nantes | - | OGC Nice | 4:1 | ||||
| 24. Round | 24/01/1981 | OGC Nice | - | Stade Lavallois | 2:1 | ||||
| 25. Round | 31/01/1981 | Nîmes Olympique | - | OGC Nice | 1:3 | ||||
| 26. Round | 07/02/1981 | OGC Nice | - | Tours FC | 2:2 | ||||
| 27. Round | 21/02/1981 | Girondins Bordeaux | - | OGC Nice | 3:0 | ||||
| 28. Round | 27/02/1981 | Paris Saint-Germain | - | OGC Nice | 3:1 | ||||
| 29. Round | 13/03/1981 | OGC Nice | - | AS Nancy Lorraine | 2:2 | ||||
| 33. Round | 20/04/1981 | OGC Nice | - | RC Strasbourg | 0:0 | ||||
| 34. Round | 04/05/1981 | Angers SCO | - | OGC Nice | 1:1 | ||||
| 35. Round | 11/05/1981 | OGC Nice | - | AJ Auxerre | 0:0 | ||||
| 36. Round | 21/05/1981 | US Valenciennes-Anzin | - | OGC Nice | 1:0 | ||||
| 37. Round | 28/05/1981 | OGC Nice | - | AS Monaco | 2:1 | ||||
| 38. Round | 01/06/1981 | FC Metz | - | OGC Nice | 0:1 |
France