| 2. Round | 24/07/2021 | Racing Club | - | Gimnasia de La Plata | 0:0 | ||||
| 3. Round | 27/07/2021 | Aldosivi | - | Racing Club | 0:2 | ||||
| 4. Round | 31/07/2021 | Racing Club | - | Sarmiento de Junín | 1:0 | ||||
| 5. Round | 09/08/2021 | Independiente | - | Racing Club | 1:0 |  |
|||
| 8. Round | 25/08/2021 | Racing Club | - | Central Córdoba SdE | 0:0 | ||||
| 9. Round | 30/08/2021 | Boca Juniors | - | Racing Club | 0:0 | |
|||
| 12. Round | 18/09/2021 | Racing Club | - | Talleres de Córdoba | 1:2 | ||||
| 13. Round | 27/09/2021 | Argentinos Juniors | - | Racing Club | 2:0 | |
|||
| 15. Round | 09/10/2021 | Patronato de Paraná | - | Racing Club | 1:2 | |
|||
| 17. Round | 19/10/2021 | Unión de Santa Fe | - | Racing Club | 1:1 | ||||
| 18. Round | 24/10/2021 | Rosario Central | - | Racing Club | 2:1 | ||||
| 19. Round | 29/10/2021 | Racing Club | - | Defensa y Justicia | 1:2 | ||||
| 20. Round | 06/11/2021 | Atlético Tucumán | - | Racing Club | 0:2 | ||||
| 21. Round | 21/11/2021 | Racing Club | - | Colón de Santa Fe | 1:2 | ||||
| 22. Round | 26/11/2021 | River Plate | - | Racing Club | 4:0 | |
|||
| 23. Round | 29/11/2021 | Racing Club | - | Lanús | 3:1 | |
|||
| 24. Round | 05/12/2021 | Huracán | - | Racing Club | 1:0 | |
|||
| 25. Round | 11/12/2021 | Racing Club | - | Godoy Cruz | 2:1 |
Argentina