| 1. Round | 07/08/2021 | Olympique Saint-Quentin | - | US Lusitanos | 2:2 | ||||
| 2. Round | 14/08/2021 | FC Metz B | - | Olympique Saint-Quentin | 0:0 |  |
|||
| 6. Round | 11/09/2021 | ASM Belfort | - | Olympique Saint-Quentin | 1:3 | |
|||
| 9. Round | 09/10/2021 | Olympique Saint-Quentin | - | AJ Auxerre B | 2:0 |
France