| 2. Round | 14/08/2021 | FC Martigues | - | Olympique Lyonnais B | 1:1 | ||||
| 3. Round | 21/08/2021 | RC Grasse | - | FC Martigues | 0:0 | ||||
| 4. Round | 28/08/2021 | FC Martigues | - | Louhans-Cuiseaux | 1:1 | ||||
| 5. Round | 04/09/2021 | Hyères FC | - | FC Martigues | 0:1 |  |
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| 6. Round | 11/09/2021 | FC Martigues | - | Lyon-La Duchère | 0:3 | ||||
| 7. Round | 18/09/2021 | AS Monaco B | - | FC Martigues | 2:0 | ||||
| 8. Round | 25/09/2021 | SC Toulon | - | FC Martigues | 0:1 | ||||
| 9. Round | 09/10/2021 | FC Martigues | - | GFA Rumilly Vallières | 3:1 | ||||
| 10. Round | 23/10/2021 | AS Saint-Priest | - | FC Martigues | 1:1 | ||||
| 14. Round | 11/12/2021 | Jura Sud | - | FC Martigues | 1:4 | |
France