| Group A | 22/10/2020 | BSC Young Boys | - | AS Roma | 1:2 | ||||
| Group A | 29/10/2020 | CFR Cluj | - | BSC Young Boys | 1:1 | ||||
| Group A | 05/11/2020 | BSC Young Boys | - | CSKA Sofia | 3:0 | ||||
| Group A | 26/11/2020 | CSKA Sofia | - | BSC Young Boys | 0:1 | ||||
| Group A | 03/12/2020 | AS Roma | - | BSC Young Boys | 3:1 |  |
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| Group A | 10/12/2020 | BSC Young Boys | - | CFR Cluj | 2:1 | ||||
| Round of 32 | 18/02/2021 | BSC Young Boys | - | Bayer Leverkusen | 4:3 |  |
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| Round of 32 | 25/02/2021 | Bayer Leverkusen | - | BSC Young Boys | 0:2 | ||||
| Round of 16 | 11/03/2021 | AFC Ajax | - | BSC Young Boys | 3:0 | ||||
| Round of 16 | 18/03/2021 | BSC Young Boys | - | AFC Ajax | 0:2 |
Congo DR