| 5. Round | 06/03/2022 | Racing Club | - | Talleres de Córdoba | 1:0 | ||||
| 6. Round | 13/03/2022 | Talleres de Córdoba | - | San Lorenzo | 0:1 | ||||
| 9. Round | 09/04/2022 | Talleres de Córdoba | - | Defensa y Justicia | 1:5 |  |
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| 10. Round | 17/04/2022 | Argentinos Juniors | - | Talleres de Córdoba | 2:1 |  |
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| 11. Round | 20/04/2022 | Talleres de Córdoba | - | River Plate | 1:0 | ||||
| 12. Round | 24/04/2022 | Banfield | - | Talleres de Córdoba | 3:1 | |
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| 13. Round | 30/04/2022 | Atlético Tucumán | - | Talleres de Córdoba | 3:0 | ||||
| 14. Round | 08/05/2022 | Talleres de Córdoba | - | Sarmiento de Junín | 1:0 | |
Uruguay