| 7. Round | 25/08/1980 | SC Bastia | - | FC Nantes | 1:2 | ||||
| 12. Round | 25/09/1980 | FC Nantes | - | US Valenciennes-Anzin | 3:0 | ||||
| 13. Round | 04/10/1980 | AJ Auxerre | - | FC Nantes | 0:0 |  |
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| 14. Round | 14/10/1980 | FC Nantes | - | FC Metz | 1:0 | ||||
| 16. Round | 30/10/1980 | FC Nantes | - | Stade Lavallois | 4:1 | ||||
| 19. Round | 22/11/1980 | FC Nantes | - | FC Sochaux | 2:1 | ||||
| 29. Round | 13/03/1981 | FC Nantes | - | RC Strasbourg | 1:1 | ||||
| 38. Round | 01/06/1981 | FC Nantes | - | Nîmes Olympique | 1:1 |
France