| 1. Round | 17/08/2024 | Stade de Reims | - | Lille OSC | 0:2 | ||||
| 2. Round | 24/08/2024 | Lille OSC | - | Angers SCO | 2:0 |  |
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| 3. Round | 01/09/2024 | Lille OSC | - | Paris Saint-Germain | 1:3 | ||||
| 4. Round | 13/09/2024 | AS Saint-Étienne | - | Lille OSC | 1:0 | ||||
| 5. Round | 21/09/2024 | Lille OSC | - | RC Strasbourg | 3:3 | ||||
| 8. Round | 18/10/2024 | AS Monaco | - | Lille OSC | 0:0 |  |
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| 9. Round | 26/10/2024 | RC Lens | - | Lille OSC | 0:2 | |
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| 10. Round | 01/11/2024 | Lille OSC | - | Olympique Lyonnais | 1:1 | ||||
| 12. Round | 24/11/2024 | Lille OSC | - | Stade Rennais | 1:0 | ||||
| 13. Round | 01/12/2024 | Montpellier HSC | - | Lille OSC | 2:2 | ||||
| 17. Round | 10/01/2025 | AJ Auxerre | - | Lille OSC | 0:0 | ||||
| 19. Round | 25/01/2025 | RC Strasbourg | - | Lille OSC | 2:1 |
France
