| 4. Round | 19/09/2021 | AS Béziers [Youth B] | - | AS Muret [Youth B] | 3:1 | ||||
| 6. Round | 03/10/2021 | Nîmes Olympique [Youth B] | - | AS Muret [Youth B] | 2:1 |  |
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| 7. Round | 09/10/2021 | AS Muret [Youth B] | - | Montpellier HSC [Youth B] | 1:4 | ||||
| 8. Round | 17/10/2021 | Rodez AF [Youth B] | - | AS Muret [Youth B] | 4:0 | ||||
| 9. Round | 24/10/2021 | AS Muret [Youth B] | - | Girondins Bordeaux [Youth B] | 0:1 | ||||
| 10. Round | 14/11/2021 | Montauban FC [Youth B] | - | AS Muret [Youth B] | 1:2 | ||||
| 11. Round | 21/11/2021 | AS Muret [Youth B] | - | Balma SC [Youth B] | 1:0 | ||||
| 12. Round | 28/11/2021 | Toulouse FC [Youth B] | - | AS Muret [Youth B] | 1:2 | ||||
| 13. Round | 05/12/2021 | AS Muret [Youth B] | - | Pau FC [Youth B] | 0:3 | ||||
| 16. Round | 06/02/2022 | AS Muret [Youth B] | - | AS Béziers [Youth B] | 1:1 |
France