| 7. Round | 18/09/2021 | FC Lorient B | - | SM Caen B | 0:1 | ||||
| 8. Round | 25/09/2021 | SM Caen B | - | FC Rouen 1899 | 2:5 | ||||
| 17. Round | 05/02/2022 | SM Caen B | - | St-Pryvé St-Hilaire | 1:4 | ||||
| 18. Round | 12/02/2022 | US Granvillaise | - | SM Caen B | 1:1 | ||||
| 20. Round | 05/03/2022 | SO Romorantin | - | SM Caen B | 0:1 | ||||
| 22. Round | 19/03/2022 | FC Rouen 1899 | - | SM Caen B | 1:0 | ||||
| 23. Round | 26/03/2022 | SM Caen B | - | EA Guingamp B | 0:2 | ||||
| 25. Round | 16/04/2022 | SM Caen B | - | AS Poissy | 0:3 | ||||
| 26. Round | 23/04/2022 | FC Versailles | - | SM Caen B | 3:0 | ||||
| 27. Round | 30/04/2022 | SM Caen B | - | C'Chartres Football | 3:0 | ||||
| 28. Round | 14/05/2022 | US Saint-Malo | - | SM Caen B | 1:0 | ||||
| 29. Round | 21/05/2022 | Châteaubriant Voltigeurs | - | SM Caen B | 0:0 | ||||
| 30. Round | 28/05/2022 | SM Caen B | - | Stade Plabennec | 2:2 |
France