| 4. Round | 28/08/2021 | Étoile FC | - | Marignane Gignac FC | 2:0 | ||||
| 5. Round | 04/09/2021 | Marignane Gignac FC | - | GOAL FC | 0:1 | ||||
| 6. Round | 11/09/2021 | Aubagne FC | - | Marignane Gignac FC | 3:0 | ||||
| 7. Round | 18/09/2021 | Marignane Gignac FC | - | Jura Sud | 1:0 | ||||
| 8. Round | 25/09/2021 | Olympique Marseille B | - | Marignane Gignac FC | 2:3 | ||||
| 9. Round | 09/10/2021 | Marignane Gignac FC | - | SC Toulon | 0:1 | ||||
| 10. Round | 23/10/2021 | Marignane Gignac FC | - | Olympique Lyonnais B | 4:0 | ||||
| 11. Round | 06/11/2021 | RC Grasse | - | Marignane Gignac FC | 2:0 |  |
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| 12. Round | 20/11/2021 | Marignane Gignac FC | - | Louhans-Cuiseaux | 2:2 | ||||
| 14. Round | 11/12/2021 | Marignane Gignac FC | - | Lyon-La Duchère | 3:0 | ||||
| 19. Round | 19/02/2022 | GOAL FC | - | Marignane Gignac FC | 1:0 | ||||
| 27. Round | 29/04/2022 | Marignane Gignac FC | - | Hyères FC | 0:0 |
Senegal